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but are only approved therapies for type 2 diabetes, not insulin resistance, per se.. Glucophage (generic Depression name is Metformin) targets defect #2: it suppresses the liver. Q: "Could you explain insulin resistance so that I can understand it?. 12 Apr 2005. Targeting Insulin
Resistance Metformin is not approved as a medication for PCOS, but is often prescribed by doctors.. A drug therapy should counteract insulin resistance and prevent or reverse its complications. Metformin reduces food intake, .. Metformin 
Can Prevent Girls with Insulin Resistance from Developing Polycystic Ovary Syndrome: Prese. 10 Sep 2007. Print - Metformin could potentially improve pregnancy
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